Neuroscience and Psychiatry
OUR RESEARCH
Our research aims to understand the neural mechanisms underlying how sensory stimuli become associated with goal directed behavior. Humans have a remarkable ability to respond with sub second precision to sensory stimuli: a dancer doing improvisation is just one example. Animal models, including rodents, are also capable of sensorimotor transformations, both innate and learned. In the Sippy lab, we utilize these models to study how sensorimotor associations shaped neural synapses and activity and how this activity drives behavior.
SELECT PUBLICATIONS
Cell-type-specific auditory responses in the striatum are shaped by feedforward inhibition. Druart M, Kori M, Chaimowitz C, Fan C, Sippy T. Cell Reports. 2024 Dec 24;44(1):115090.
Cell Type-Specific Membrane Potential Changes in Dorsolateral Striatum Accompanying Reward-Based Sensorimotor Learning..Sippy T, Chaimowitz C, Crochet S, Petersen CC. FUNCTION 2021 Sept 21; 10.1093
Cell-Type-Specific Sensorimotor Processing In Striatal Projection Neurons During Goal-Directed Behavior. Sippy, Tanya; Lapray, Damien; Crochet, Sylvain; Petersen, Carl C H. Neuron. 2015 Oct 21; 88(2):298-305
Fast Nonnegative Deconvolution For Spike Train Inference From Population Calcium Imaging. Vogelstein, Joshua T; Packer, Adam M; Machado, Timothy A; Sippy, Tanya; Babadi, Baktash; Yuste, Rafael; Paninski, Liam. Journal Of Neurophysiology. 2010 Dec; 104(6):3691-704
Acute Changes In Short-Term Plasticity At Synapses With Elevated Levels Of Neuronal Calcium Sensor-1. Sippy, Tanya; Cruz-MartÃn, Alberto; Jeromin, Andreas; Schweizer, Felix E.
Nature Neuroscience. 2003 Oct; 6(10):1031-8
CONTACT
The Sippy Lab
NYU Medical Center Science Building
435 East 30th Street
10th Floor
New York, NY 10016
Tanya.Sippy@nyulangone.org
